一、资源保障体系
研发全海深微生物保压富集培养装置，基于微流控技术建立细胞的超高通量筛选、评价、检测的全链条装备体系；建立深海未（难）培养微生物的培养技术体系，建立深海微生物代谢产物和新型酶的定向/高效挖掘和表达技术，强化深海微生物战略资源获取能力；建设“菌种-功能基因-天然产物”一体化资源库与数据开放共享平台，形成“样本-数据-信息”全链条保障，为上海生物制造产业提供源动力。
二、技术研发体系
建立高通量功能筛选与基因组编辑平台，开发适配深海微生物的CRISPR-Cas工具，精准解析未知基因功能；融合人工智能与多组学技术，构建“数据驱动-智能筛选-实验验证”闭环，助力上海人工智能与生命科学交叉创新。
三、产业转化体系
以合成生物学推动深海活性物质开发，与海洋生物制品、大健康领域龙头企业共建创新联合体，推进产业化落地，赋能上海海洋生物制药与大健康产业高质量发展，为深海生物经济产业集群注入动能。
四、标准与战略价值
强化知识产权全流程管理，参与制定深海微生物领域行业标准和国家标准，构建自主技术规范体系，提升我国海洋生物产业国际竞争力，助力上海打造全球海洋中心城市与国际科创中心，支撑海洋科技自立自强。
1. Resource Support System
Developing full-ocean-depth pressure-retaining microbial enrichment devices to overcome the bottleneck in culturing uncultured/difficult-to-culture microorganisms and enhance the capacity for acquiring deep ocean strategic bioresources; establishing an integrated resource repository of microbes - functional genes - natural products and an open-access shared data platform, forging a full-chain support system covering sample-data-information to provide source power supporting Shanghai's biomanufacturing industry.
2. Technological R&D System
Establishing a high-throughput functional screening and genome editing platform; developing CRISPR-Cas tools adapted to deep ocean microorganisms for precise analysis of unknown gene functions; integrating artificial intelligence and multi-omics technologies to build a closed loop of data-driven - intelligent screening - experimental verification, supporting interdisciplinary innovation in artificial intelligence and life sciences in Shanghai.
3. Industrial Transformation System
Leveraging synthetic biology to advance the development of deep ocean bioactive products; establishing innovation consortia with leading enterprises in marine biological products and big health sectors; advancing industrial applications of relevant technologies to empower the high-quality development of Shanghai's marine biopharmaceutical and big health industries and inject momentum into Shanghai's deep ocean bioeconomy.
4. Standards & Strategic Value
Strengthening the whole-process management of intellectual property; participating in the formulation of industrial standards and national standards in the deep ocean microbiology; establishing an independent technical specification system; enhancing China's international competitiveness in the marine biological industry; supporting Shanghai in building a global ocean center city and an international sci-tech innovation center, and underpinning the self-reliance and self-improvement in marine science and technology.
